Aisha Chaudhary narrates the story of her parents Moose (her mother) and Panda (her father) from the afterlife. Aditi Chaudhary and Niren are a young couple who come from different backgrounds; Aditi is from a salubrious suburb in South Delhi whereas Niren is from a grounded middle-class family. The couple are in love and have "an active sex life", according to Aisha's narration. The couple get married and Aditi becomes pregnant with their first child Tanya Chaudhary, who dies within months of her birth due to the severe combined immunodeficiency condition. Baby Tanya was frequently ill and, while Aditi was convinced it was a serious issue, Niren dismissed it as trivial. Niren believed negligence was the reason Tanya could not be treated sooner and blamed himself for the death of his child. As Aditi mourned the death of her child, she was consoled by a Catholic nun and decided to be baptized.
Aditi and Niren have a second child named Ishaan. A few years later, Aditi bore their third child, a girl named Aisha. They later learn Aisha has the same medical condition as their first child and are heartbroken. After the doctors in Delhi give up on Aisha's treatment, the couple go to London where they learn the disease could be treated with a very costly bone marrow transplant. Niren starts working to earn the money while also asking for crowdfunding via a radio station. After several weeks, they learn several people have donated money for Aisha's treatment. The surgery is successful but Aisha is kept under doctor's watch. Aditi decides to stay in London while Niren returns to India with his family and his son Ishaan. Aditi grows overprotective of Aisha, cleaning the apartment and other items to keep Aisha away from any infection. Ishaan starts missing his mother while Niren is always thinking about Aditi and Aisha. This also starts affecting Aditi and Niren's relationship as Aditi is always occupied with Aisha and taking care of her. Months go by and Niren goes to London and asks Aditi to move back to India so that their relationship is not affected. He reasons with Aditi on the grounds that Aisha had gotten better and occasional doctor's visit can be done in India as well. Aditi tells him that they have to live here for a very long time as per doctor's recommendation till Aisha's condition is cured. The whole family moves here permanently till Aisha is cured. Niren's career grows in London and he becomes rich and their family becomes affluent. What happened to Aisha later? Watch Sky Is Pink to know!
Priyanka Chopra shot for the movie until 4 days before her wedding.
Zaira Wasim (Aisha) requested the producers to keep her away from films promotion as she had decided to quit films.